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Melanie Werst

Senior Lecturer in Chemistry



1985 - 1989 Northwestern University, Evanston, IL
Ph.D. in Physical Chemistry (GPA: 3.9/4.0)
Awards National Biomedical ESR Center Trainees/zip,
Medical College of WI, 1988
Gray Freshwater Institute Biological Traineeship,
University of Minnesota, 1986

1981-1984 University of Minnesota, Minneapolis, Minnesota
13.S. in Chemistry, GPA: 3.4/4.0

1978 - 1980 Cambridge University Advanced Level Examinations
Physics, Chemistry, Mathematics, GPA: 3.7/4.0,
Distinction: National Science Scholarship

Selected Publications

Mode of Substrate Carboxyl Binding to the [4Fe-4S) + Cluster of Reduced Aconitase as Studied by 170 and 13C Electron-Nuclear Double Resonance Spectroscopy”, M. C. Kennedy, M. Werst, J. Telser, M. Emptage, H. Beinert and B. M. Hoffman, (1987) Proc Natl. Acad. Sci USA 84, 8854.

“Electron-Nuclear Double Resonance (ENDOR) of Mctalloenzymes’, B. M. Hoffman, R. J. Gurbiel, M. Werst and M. Sivaraja, in Advances in EPR in Biology and Biochemistry (1989) 541-591. A. Hoff, ed., Elsevier Science Publishers: Amsterdam.

-170, 1H, and 2H Electron-Nuclear Double Resonance Characterization of Solvent, Substrate and Inhibitor Binding to the [4Fe.4S]+ Cluster of Aconitase”, M. Wersi, M. C. Kennedy, H. Beinert and B. M. Hoffman, (1990) Biochem. 29, 10526.

“Characterization of the [4Fe-4S] + Cluster at the Active Site of Aconitase by 57Fe, 33S, and 14N Electron-Nuclear Double Resonance Spectroscopy”, M. Werst, M. C. Kennedy, FL. Beinert and B. M. Hoffman, (1990) Biochem. 29, 10533.

“Ligand Spin Densities in Blue Copper Proteins by 0-Band 1H and 14N ENDOR Spectroscopy”, M. Werst, C. E. Davoust and B. M. Hoffman, (l991)J Am Chem. Soc., 113 1533.

“Energy Transfer and Trapping in the Photosystem 1 Core Antenna: A Temperature Study”, M. Wcrst, Y. Jia, L. Mets and G. Fleming, (1992) Biophys J. 61, 868.

“Simulations of the Temperature Dependence of Energy Transfer in the Photosystem I Core Antenna”, Y. Jia, J. Jean, M. Werst, C. -K. Chan and 0. Fleming, (1992) Biophys J. 63, 259.

“14’15N, 13c, 57Fe,1’2H Q-Band ENDOR Study from Fe-S Proteins with Clusters That Have Endogenous Sulfur Ligands”, A. L. P. Houseman, B. -H. Oh, M. C. Kennedy, C. Fan, M. M. Werst, H. Beinert, J. L. Markley and B. M. Hoffman, (1992) Biochem. 31, 2073.

“Detection of Two Histidine Ligands to CUA of Cytochrome c Oxidase by 35-0Hz ENDOR: 14’15N and 63’65Cu ENDOR Studies of the CUA Site in Bovine Heart Cytochrome aai and Cytochromes cam and ba3 from Thennus Therinophilus”, R.J. Gurbiel, Y. Fan, K. K. Surerus, M. Werst, S. M. Musser, P. E. Doan, S. 1. Chan, J. A. Fee and B. M. Hoffman, (1993) J Am Chem. Soc. 115, 10888.

“Quinone Exchange at the Al site in Photosystem I”, A. Barkoff, N. Brunkan, S. Snyder, A. Ostafin, M. Werst, J. Biggins, and M. C. Thurnauer, Proceedings 10th International Photosynthesis Congress Montpellier, France, August 20-25, 1995.

“Nuclear Quantum Beats Observed from Photosynthetic Charge Separation”, S. Weber, M. Werst, M. Thurnauer, J. R. Norris, E. Ohmcs, G. Kothe, 210th National Meeting of ACS Chicago, IL, August 20-25, 1995.

‘EPR Study of Structure of the Primary Reactants in Photosystem 1”, A. E. Ostafin, M. M. Werst, M. C. Thurnauer, 210th National Meeting of ACS Chicago, IL, August 20-25, 1995.