Dr. LaDu’s current research is focused on Alzheimer’s disease and the role that two proteins – amyloid-ß (Aß) and apolipoprotein E (apoE) – play in Alzheimer’s disease pathology. It is known that people who carry a naturally occurring version of the apoE gene (called apoE4) have a 60-fold increase risk of developing Alzheimer’s, while neuronal accumulation of amyloid-ß is known to cause of Alzheimer’s disease. Dr. LaDu’s research explores how these two proteins interact to compromise neuronal function. Her research utilizes an integrated approach to address the complexity of apoE/Aβ interactions, including biochemical, molecular biology, and cell biology methods using in vitro, ex vivo, and in vivo models.
Dr. LaDu has served on the faculty at the University of Illinois at Chicago since 2005. She received her BA in history from Grinnell College and her Ph.D. in physiology and biophysics at University of Illinois at Chicago. She conducted her postdoctoral fellowship at the University of Chicago Medical Center.
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