Shubhik DebBurman

imageProfessor of Biology
Chair, Neuroscience Program

Education

Postdoctoral Fellow, Molecular Genetics and Cell Biology, University of Chicago
PhD, Neuroscience, Northwestern University
BA, Biology and Economics, Wittenberg University

Specialization

Neuroscience
Cell and Molecular Biology
Biochemistry
Molecular Genetics
Pharmacology

Interests

  • Biology of protein folding, misfolding and degradation
  • Biology of cellular stress responses and cell death
  • Biology of diseases linked to protein misfolding and clearance
  • Teaching innovations & experiential learning in science education
  • Development of assessment tools for science pedagogy
  • Integration of scholarship & service with teaching to strengthen student scholarship

Courses Taught

First-Year Studies 106: Medical Mysteries of the Mind
Biology 130: Biology Inquiry Deadly Shapes, Hostage Brains
Biology 221: Molecules, Genes, & Cells (Cell & Molecular Biology)
Biology 291: Tutorial
Biology/Neuroscience 324: Advanced Cell Biology
Biology/Neuroscience 346: Molecular Neuroscience
Biology/Neuroscience 362: Mechanisms of Brain Dysfunction
Biology/Neuroscience 480: Neural Frontiers (Senior seminar)
Biology 492: Independent Research Colloquium
Biology 493: Independent Study
Biology 494: Senior Thesis

Past Course Developmental Experience

Biology of Disease
Advanced Topics in Neurobiology
Advanced Topics in Cell Biology
Neurobiology: From Molecules to Behavior

Positions Held

2012-present, Professor, Biology Department, Lake Forest College

2009-present, Chair, Neuroscience Program, Lake Forest College

2006-2012, Associate Professor, Biology Department, Lake Forest College

2001-2006, Assistant Professor, Biology Department, Lake Forest College

1998-2001, Visiting Assistant Professor, Biology Department, Kalamazoo College

1997-1998, Research Associate, Howard Hughes Medical Institute, The University of Chicago (Mentor: Susan Lindquist)

1996-1997, Postdoctoral Fellow, Department of Molecular Genetics and Cell Biology, University of Chicago  (Mentor: Susan Lindquist)

1996, 1997 Visiting Scientist & Volunteer, NIH-NIAID Rocky Mountain National Laboratories (Collaborator: Byron Caughey)

1994-1996 Graduate Scholar, Northwestern University (Mentor: Marlene Hosey)

1992-1993 Teaching Fellow, Northwestern University Institute of Neuroscience

1991-1992, University Fellow, Northwestern University

Grants and Fellowships

2013 Parkinson’s Disease Foundation Grant $4000 (for undergraduate training: Natalie Kukulka ’13)

2007-2012 National Institutes of Health Academic Research Enhancement Award (NIH R15 AREA) Grant, $207,571

2009-2010 NIH American Recovery and Reinvestment Act ARRA Undergraduate Research AREA Supplement $14,514 (for undergraduate training: Daniel Sanchez ’11 and Keith Solvang ’11)

2008-2010 American Parkinson Disease Association Individual Investigator Grant $50,000

2009 Parkinson’s Disease Foundation Grant $3000 (for undergraduate training: Michael Fiske ’10)

2007 Parkinson’s Disease Foundation Grant $1700 (for undergraduate training: Lokesh Kukreja ’08)

2004-2007 National Institutes of Health Academic Research Enhancement Award (NIH R15 AREA) Grant, $195,810

2004-2005 NIH AREA Research Supplement $25,708 (for undergraduate training: Sara Herrera ’05)

2005, 2004, 2003, 2000 ASBMB Undergraduate Faculty Research Travel Awards, Experimental Biology Meeting

2004 Parkinson’s Disease Foundation Grant $2000 (for undergraduate training: Isaac Holmes ’05)

2004 Council of Undergraduate Research (CUR) summer grant $3000 (for undergraduate training: Nijee Sharma ’04)

2004 Lake Forest College Learning and Teaching Center Pedagogical Innovation Grant $4000 (Creation of an Integrated Teaching & Research Cell Imaging & Culturing Facility Johnson 240)

2003-2007 National Science Foundation Curriculum, Course, & Laboratory Improvement (CCLI) Grant, $141,878 including 1:1 match by LFC

2003 Council of Undergraduate Research Fellowship Award $3500 (for undergraduate training: Nijee Sharma ’04) (2003)

2001-2004 National Science Foundation Major Research Instrumentation Grant, Lake Forest College (Co-PI with three LFC colleagues) $94,000

2000 Michigan Parkinson Foundation, Ann Arbor, MI $4500 (for undergraduate training: Aash Bhatt ’01)

1999-2001 Neurological Disorders Grant, Campbell Foundation, Grand Rapids, MI $65,700

1998-2001 McGregor Research Grant, Kalamazoo College, Michigan $20,000

1997-2000 Howard Hughes Medical Institute Fellowship of the Life Sciences Research Foundation ($35000/year).  Institutions: Life Sciences Research Foundation (LSRF) & Howard Hughes Medical Institute (voluntarily declined after 1998 to pursue faculty career)

1996-1997 Charles Webster Postdoctoral Fellow (awarded by the University of Chicago Cancer Research Foundation)

1994-1996 Advanced Predoctoral Fellow in Pharmacology & Toxicology. Institution: Pharmaceutical Research Manufacturers of America Foundation (PRMAF)

1983-1987 National Talent Search Scholar, National Council of Education, Research & Training, Delhi, INDIA (Premier merit scholarship in India awarded annually to 250 college-bound students)

Honors

2009 The Bird Award for Intellectual Contributions to the Campus Community, Lake Forest College

2006 Outstanding Service Citation in Undergraduate Neuroscience Education, Chicago Chapter Society for Neuroscience
 
2004 William L. Dunn Award for Outstanding Teaching & Scholarly Promise, Lake Forest College

2004 F21 Faculty For the 21st Century, Project Kaleidoscope 

2004 Hotchkiss Fellow, Lake Forest College (one semester competitive leave for scholarship)
 
1998 The Outstanding Young Alumnus Award, Wittenberg University, Springfield, OH (First Wittenberg alumnus to receive this award given annually since 1998 for professional achievements that reflect Wittenberg’s ideals)

1998 American Society of Cell Biology (ASCB) Selected Biomedical Abstract (Among the 10 selected for press release from over 3000 abstracts presented at the 1998 ASCB meeting)

1996 Schiff-Kahn Prize in Molecular Pharmacology & Biological Chemistry Northwestern University Medical School, Chicago, IL
(Award for outstanding Ph.D. dissertation in molecular pharmacology and biological chemistry)

1996 Student Speaker representing Northwestern University, Graduate Student Symposium Annual Meeting of the Chicago Chapter, Society for Neuroscience, Chicago, IL
 
1994 1st Place Honors-Student Research Poster Competition, Annual meeting of the Great Lakes Chapter- American Society Pharmaceutics and Experimental Therapeutics (ASPET), Chicago, IL
 
1994 Gramm Student Research Travel Award, Northwestern University Medical School, Chicago, IL
 
1994 Sigma Xi Graduate Research Prize - 2nd Place honors, Northwestern University, Evanston, IL
 
1991 John F. Mitchell Award, Wittenberg University, Springfield, OH
(Awarded to graduating male senior best exemplifying the liberal arts at Wittenberg University)

1990-91 President, Wittenberg University Student Government
 
1990 Beta Beta Beta (national biology honorary) & Phi Alpha Theta (national history honorary), Wittenberg University, Springfield, OH
 
1990 Student Leader of the Year, Wittenberg University, Springfield, OH (Annual award to a student for outstanding campus leadership)
 
1989 Omicron Delta Kappa Academic Excellence & Service Award, Wittenberg University, Springfield, OH

Service (beyond the college)

2013-2015 President, Chicago Chapter Society for Neuroscience (http://www.chicagosfn.org; also President-elect, 2012-2013; Councilor, 2010-2012)

  • organized postdoctoral session at annual meeting 2011 and graduate student symposium in annual meeting 2012 and 2013

2014-2015 LFC Faculty Mentor, Teacher-Scholar Program at Rosalind Franklin University of Medicine and Science

2008-present, Coordinator, LFC-RFUMS Summer Research Scholars program
(2012-present, Co-cordinator)

2014 External Faculty Reviewer, for the Neuroscience Program, Skidmore College, New York

2011 External Faculty Reviewer, for the Biology Department, Gustavus Adolphus College, Minnesota

2001-present, Faculty Mentor for the Preparing Future Faculty (PFF) Program and Graduate Teaching Certification Program, Northwestern University

2001-present, Regular Panelist, Bio-Opportunities Program, Northwestern University

2010-2013 (also 2008-2010) Member, Education Committee, American Society of Cell Biology (ASCB; http://www.ascb.org)

2008-2010 Councilor, Great Lakes Chapter- American Society of Pharmaceutical & Experimental Therapeutics
(GLC-ASPET; http://www.aspet.org/public/chapters/gl_chapter.html)

  • served as undergraduate liaison: founded and organized the first undergraduate sessions (2009, 2010) and co-organized the first postdoctoral sessions at annual meeting (2010)

2004-present, Regular faculty session chair, Annual Argonne National Labs Undergraduate Research Symposia

2002-2006 Member, Executive Council, Chicago Chapter Society for Neuroscience (http://www.chicagosfn.org

  • served as first undergraduate liaison, and founded and organized undergraduate sessions at annual meeting (2003-2006)

2004-2006 Councilor, Faculty for Undergraduate Neuroscience (http://www.funfaculty.org)
 
2005 (and 2004), Grant Reviewer, National Science Foundation, Curriculum, Course, and Laboratory Improvement (CCLI) Program
 
2005 (and 2004), Judge, Undergraduate Research Symposium, Annual meeting of the American Society of Biochemistry & Molecular Biology (ASBMB; http://www.asbmb.org)
 

Memberships

Chicago Chapter Society for Neuroscience
ASPET- Great Lakes Chapter

Society for Neuroscience
American Society for Cell Biology 
American Society of Biochemistry & Molecular Biology
Faculty for Undergraduate Neuroscience
Project Kaleidoscope (PKAL)
Nu Rho Psi

Faculty Advisor to Lake Forest College student organizations:
Nu Rho Psi,
2012-present (founding advisor)*National Chapter of the Year 2013
Synapse
, 2009-present (founding advisor)
Eukaryon
, 2004-2007, 2009-2011, 2013-present (founding advisor)
Beta Beta Beta
, 2008-2010
UAN-ASBMB, 2008-2009 (founding co-advisor)

Manuscripts in Preparation and Current Projects

Undergraduate Authors (asterisked)

Senagolage, M*, Perez, J*, Ayala, A*, Vahedi, M*, Price, J*, Fiske, M*, Khan, R*, Tembo, M*, and DebBurman, SK. Complex regulation of alpha-synuclein pathological properties in yeasts by endocytosis genes.

Konnikova, A*, Choi, R*, Sanchez, D*, Ahlstrand, K*, Sullivan, P*, Perez, J*, and DebBurman, SK. Autophagic regulation of alpha-synuclein membrane association, aggregation and toxicity in budding yeast.

DebBurman, SK, Reich A*, Rizvydeen*, S, Konnikova, A*, Fiske, M*, Davis, S*, Pore, S*, Zorniak, M*, Brandis, K*, Smith, P., and Menke, S. EUKARYON: An undergraduate peer-reviewed life sciences journal that strengthens an inquiry-based biology curriculum and supports and community of students as scholars.

DebBurman, SK.  Learning How Scientists Think: Role-Playing Famous Neuroscientists in an Undergraduate Neuroscience Course.

DebBurman, SK. An advanced cell biology course designed for undergraduates to propose, conduct, and publish original biomedical research.

Current Projects

Solvang, K*, Fiske, M*, DebBurman, SK. Alpha-synuclein nitrosylation regulates aggregation and cellular toxicity in budding yeast.

Kukulka, N*, DebBurman, SK. Combination mutant analysis of familial Parkinson’s disease  alpha-synuclein mutants in two yeast models: Not all mutants are equal.

Campbell, K*, Lipkin, G*, Solvang, K*, DebBurman, SK. Amino acid determinants of alpha-synuclein membrane association, aggregation and toxicity.

Lipkin, G*, Hamid, K*, Campbell, K*, DebBurman, SK. Evaluation of alpha-synuclein sumoylation in yeasts.

Tembo, M*, Munoz M*, DebBurman, SK. Evaluation of H50Q and G51D familial alpha-synuclein familial mutants in yeast.

Kukulka, N*, Hamid K*, Bello Rojas S*, DebBurman, SK. Evaluation of alpha-synuclein splice variants in yeast.

Alvarado, C*, Chiren, S*, James, J*, Roman, A*, Munoz, M*, Campbell, K*, and DebBurman, SK. Evaluation of alpha-synuclein C-terminal truncations in yeast.

Publications

Undergraduate Authors (asterisked)

2011 Fiske, M*#, Valtierra, S*,# Solvang, K*, Zorniak, M*, White, M.*, Herrera, S*, Brezinsky, R*, Konnikova, A* and DebBurman, SK. Contribution of serine phosphorylation and alanine-76 to alpha-synuclein membrane association and aggregation in yeast models.  Parkinson’s Disease Volume 2011, 12 pages, Article ID 392180; doi:10.4061/2011/392180. #: co-first authors.

2011 Fiske, M*#, White M*#,  Valtierra, S*, Herrera, S*, Solvang, K*, Konnikova, A* and DebBurman, SK. E46K Alpha-Synuclein Familial Mutant Binds Membranes, Aggregates, and Induces Strain-Selective Toxicity in Yeast Models. ISRN Neurology, vol. 2011, Article ID 521847, 14 pages, 2011. doi:10.5402/2011/521847. #: co-first authors.

2006 Sharma, N*#, Brandis, K*#, Herrera, SK*, Johnson, BE*, Vaidya, T*, Srestha R*, and DebBurman, SK. (2006) Alpha-Synuclein Budding Yeast Model: Toxicity Enhanced By Impaired Proteasome and Oxidative Stress. Journal of Molecular Neuroscience 28, 171-178. #: co-first authors

2006 Brandis, K*, Holmes, I*, England, S*, Sharma, N*, Kukreja, L*, and DebBurman, SK. Alpha-Synuclein Fission Yeast Model: Concentration-Dependent Aggregation Without Membrane Localization or Toxicity. Journal of Molecular Neuroscience 28, 179-192.

2002 DebBurman, S.K. Learning How Scientists Work: Experiential research projects to promote cell biology learning and scientific process skills. Cell Biology Education 1, 154-172.

1999 Caughey, B, Chabry, J, Hermann, L, Demaimey, R, Raymond, G, Raymond, L, DebBurman, SK, Lindquist, SL, & B Chesebro. Formation of protease-resistant prion protein: Stimulation and inhibition, in Alzheimer’s Disease and Related Disorders (Edited by K Iqbal, DF Schwab, B Winblad, and HM Wisniewski), John Wiley & Sons, 581-587.

1998 Lindquist, SL, DebBurman, SK, Glover, JR, Kowal, AK, Liu, J, & TC Serio.  Amyloid fibers of Sup35 support a prion-like mechanism of inheritance in yeast. Biochemical Society Transactions 26, 486-90.

1997 DebBurman, SK, Raymond, GJ, Caughey, B, & SL Lindquist (1997) Chaperone-supervised conversion of prion protein to its protease-resistant form. Proceedings of the National Academy of Sciences USA. 97, 13938-13943.

* Highlighted as Nature News & Views: by Welch, WJ, and P Gambetti.
Nature 392, 23-24 (1998)
* Highlighted in New Scientist This Week by Philip Cohen. New Scientist 2112, December 13, 1997, p8.
* Highlighted in Folding & Design 3, 1998, R41 (as a new paper alert).

1996 Hosey, MM, DebBurman, SK, Pals-Rylaarsdam, R, & JL Benovic.  The Role of G protein-coupled receptor kinases in the regulation of muscarinic cholinergic receptors, in “Cholinergic mechanisms: From Molecular Biology to Clinical Significance” (Proceedings of the Ninth International Symposium on Cholinergic Mechanisms), Progress in Brain Research (Editors: K. Loffelholz and K. Klein), Elvesier, 236-253.

1996 DebBurman, SK, Ptasienski, J, Benovic, JL, & MM Hosey.  G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that is conditionally activated by G protein beta-gamma subunits.  Journal of Biological Chemistry  271, 22552-22561.

1995 Hosey, MM, Benovic, JL, DebBurman, SK, & RM Richardson.  Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors, Proceedings of the Sixth International Symposium on Subtypes of Muscarinic Receptors) Life Sciences 11/12, 951-955.

1995 DebBurman, SK, & MM Hosey. Role of Protein Phosphorylation in the Desensitization of Muscarinic Cholinergic Receptors, in Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function (Editor: J. Wess), R.G. Landes Company, Biomedical Publishers, Austin, USA, 209-226.

1995 DebBurman, SK, Ptasienski, J, Boetticher, E., Lomasney, JW, Benovic, JL, & MM Hosey.  Lipid-mediated regulation of G protein-coupled receptor kinases GRK2 & GRK3. Journal of Biological Chemistry 270, 5742-5747.

1995 DebBurman, SK, Kunapuli, P, Benovic, JL, & MM Hosey. Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. Molecular Pharmacology 47, 224-233.

Student Publications in Undergraduate Journals

Note: the papers below were published in national peer-reviewed undergraduate journals

2009 Kukreja, L*, and DebBurman, SK. Oxidants Induce alpha-Synuclein-Independent Toxicity in a Fission Yeast Model for Parkinson’s Disease. Journal of Young Investigators. Volume 19, Issue 17 on 03 November.  (http://www.jyi.org/research/re.php?id=3529)

2008 Kukreja, L* (Faculty Advisor: DebBurman, SK.) Evaluating alpha-synuclein’s interaction with cellular phospholipids and potential toxicity in yeast models for Parkinson’s disease. AJUR: The Journal for Undergraduate Research in the Pure and Applied Sciences, Vol 7, 9-24.

2007 Zorniak, M* & Brandis, K* (Faculty Advisor: DebBurman, SK.) Can Oxidative Stress and Mitochondrial Dysfunction Enhance alpha-synuclein Toxicity in a Yeast Model of Parkinson’s Disease? Journal of Young Investigators Vol 17, issue 6. WebID: http://www.jyi.org/articletools/print.php?id=1350

2006 Paul, AG* (Faculty Advisor: DebBurman, SK.)  Evaluation of STP2-dependent alpha-synuclein toxicity in a budding yeast model: Is GAPDH involved? Impulse: Impulse: An Undergraduate Journal in Neuroscience.

Invited Talks

2014 “Undergraduates drive insights into Parkinson’s Disease using yeast models”, University of Chicago

2014 “The Juggling Act of a Small College Professor: Why be one and how to prepare for it”, University of Chicago

2013 “Undergraduates drive insights into Parkinson’s Disease using yeast models”, Neuroscience Graduate Program, University of Wisconsin - Madison

2013 “The Juggling Act of a Small College Professor: Why be one and how to prepare for it”, Neuroscience Graduate Program, University of Wisconsin - Madison

2013 “Preparing for a Career as a Liberal Arts College Professor: The Nuts and Bolts”, Molecular & Environmental Toxicology Program, University of Wisconsin - Madison

2012 “Yeasts and Undergraduates help Understand Parkinson’s Disease Pathology”, University of Buffalo, Buffalo, NY

2012 “Preparing for a Career as a College Professor: Juggling Three Hats” University of Buffalo, Buffalo, NY

2012 “Careers: Teaching & research at a small liberal arts college” Northwestern University, IL

2011 “Value of an undergraduate liberal arts education at a small college in the United States”, at several high schools in India, including Delhi Public School (Gurgaon), Heritage School (Gurgaon), American Embassy School (New Delhi), United World Colleges Mahindra (Pune), KIIT University (Bhubaneswar)

2011 “New Insights into Parkinson’s Disease from Yeast Models”, Rosalind Franklin University of Medicine and Science, North Chicago, IL

2011 “Preparing for a Career as a College Professor: Teacher, Scholar, & Citizen”, Rosalind Franklin University of Medicine and Science, North Chicago, IL

2011 “How Undergraduates use Yeasts to Drive New Insights into Parkinson’s disease”, Roosevelt University, Chicago, IL

2011 “Modeling a Protein Misfolding Disease in Yeasts”. Dominican University, River Forest, IL

2009 “Tips to Start and Sustain a Student-Centered Research at a Liberal Arts College”, American Society of Cell Biology Meeting, San Francisco, CA

2008 “The Job Search & Interview Process”, Panelist, Northwestern University Directions Professional Development Conference, Evanston, IL

2008 “The Job Search & Interview Process”, Panelist, Preparing Future Faculty Workshop, Oakton Community College, IL

2008 Tips to Start and Sustain a Student-Centered Research at a Liberal Arts College, American Society of Cell Biology Meeting, San Francisco, CA

2008 “Insight into Parkinson’s Disease From Yeast Models”, Rush Medical College/Rush University

2008 “The 21st Century College Professor: Teacher, Scholar, & Citizen”, Rush Medical College/Rush University

2007 “A Faculty Career At a Liberal Arts College”. Careers in Pharmacology Workshop, Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting

2005  A Toxic Shape, A Tragic Consequence: Yeasts & Undergraduates Help Understand Parkinson’s Disease, Skidmore College

2005 “Modeling Parkinson Disease: Two Yeasts, Distinct Insights”
Loyola Stritch School of Medicine, IL

2005 “Mentoring Preparing Future Faculty Fellows in Biology at Lake Forest College”, Northwestern Feinberg School of Medicine

2005 “Careers: Teaching & research in a small liberal arts college” Loyola Stritch School of Medicine, IL
 
2005 “Integrating Teaching, Scholarship, & Service to Strengthen Undergraduate Student Scholarship”, Pedagogies of Engagement, An American Association of Colleges & Universities (AACU) Meeting, Bethesda MD

2004 “Protein Misfolding & Neurodegeneration: Insights from Chaperones and Yeast”, Purdue University, West Lafayette, IN

2004 “Pedagogical Scholarship: Translating Philosophy Into Practice” Purdue University, West Lafayette, IN

2004 “Insights into Prion Disease and Parkinson Disease from Chaperones & Yeasts”, University of Illinois at Chicago, IL

2004 “Probing Yeasts to Gain Insight Into Neurodegeneration Linked to Parkinson Disease”, Rosalind Franklin University/Chicago Medical School, IL

2004 “Protein Misfolding & Neurodegeneration: Insights from Chaperones and Yeast”, Purdue University, Calumet City, IN

2004 “A Career as a College Professor: The Specifics of How To Get To Where You Want To Be”, American Society of Pharmaceutical & Experimental Therapeutics (ASPET) Committee on Minorities Affairs, Annual Meeting of Experimental Biology, Washington, DC

2004 “Careers: Teaching & research in a small liberal arts college” Northwestern University, IL

2002 “The Small Liberal Arts College: Is this for You?”
(Beyond Books Series discussion on Alternate Careers in Academia, Preparing Future Faculty Program), Northwestern University, IL
 
2000 “Combating Neurodegeneration”, Biology Department, Lake Forest College, IL

2000 “Combating Diseased Protein Shapes With Molecular Chaperones”, Biology Department, Grinnell College, IA

2000 “Deadly Protein Shapes In Human Disease”, Joint Sciences Department, Claremont Colleges, CA

1999 “Combating Diseased Protein Shapes With Molecular Chaperones”, Department of Biology, Macalester College, MN

1999 “Careers: Teaching & Research In A Small Liberal Arts College” (A Bio-Opportunities Workshop) Northwestern University Medical School, IL

1999 “Diseased Protein Shapes: Combating Them With Molecular Chaperones”, Department of Biology, Western Michigan University, MI

1999 “Combating Neurodegenerative Diseases With Molecular Chaperones”, Faculty Seminar Series, Kalamazoo College, MI

1999 “Combating Neurodegenerative Diseases With Molecular Chaperones”, Department of Biology, Hope College, MI

1998 “Prions: Novel Agents Of Genetic Inheritance And Infectious Disease”, Pharmacia-Upjohn Company, Kalamazoo, MI

1998 “Molecular Chaperones & Mammalian Prion Formation”
BIOMEDICINE Meeting-American Federation of Medical Research, Washington DC

1998 “Prions: Agents Of Mad Cow Disease”, Department of Biology, Kalamazoo College, MI

1998 “Do Prions Cause Mad Cow Disease?”, Department of Biology, Alma College, MI

1997 “An Expanding World Of Prions”, NIH Rocky Mountain Laboratories, Hamilton, MT

1997 “Molecular Chaperones & Misfolded Proteins: Implications In Neurodegenerative Disease”, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, MD

1997 “Protein Conformation Switches: In Health & Disease”, Department of Biology, Wittenberg University, Springfield, OH

1997 “Mad Cow Disease: Can We Cure It?”, Department of Biology, Lake Forest College, IL

Other Talks

2002 “Experiential research projects promote learning an inquiry-based undergraduate science curriculum”, Undergraduate Research Network, National Council of Undergraduate Research, Whitewater, WI

1997 “Molecular chaperones modulate prion conformation switch” Midwest Stress Response & Chaperones Conference, Chicago, IL

1996 “Phosphorylation and regulation of G protein-coupled receptors” Department of Molecular Pharmacology & Biological Chemistry, Northwestern University Medical School, Chicago, IL

1995 “Lipid mediated regulation of G protein-coupled receptor kinases GRK2 and GRK3”, Graduate Research Symposium, Society for Neuroscience-Annual meeting of the Chicago Chapter, Chicago, IL

1995 “Molecular basis of homologous desensitization of G protein-coupled receptors”, Howard Hughes Medical Institute, University of Chicago, IL

1995 “G protein-coupled receptor regulation by protein phosphorylation”, Department of Biochemistry, Molecular Biology & Biochemistry, Northwestern University, IL

Posters

Undergraduate co-authors asterisked. Where possible, the lead undergraduate(s) present the poster.

2014 Evidence of Endocytic Regulation of Alpha-Synuclein Aggregation and Toxicity: Insights from yeast.  M. Tembo*, M. Senagolage*, J. Perez*, A. Ayala*, S. DebBurman. Chicago Society for Neuroscience Meeting, Illinois
(Third Prize to M. Tembo ’15, Undergraduate Poster)

2014 Two stories about Parkinson’s Disease Protein, alpha-Synuclein: Truncations and Amino acid determinants. K. Campbell*, M. Munoz*, C. Alvarado*, S. Chiren*, J. James*, A. Roman*, G. Lipkin*, and S. DebBurman. Chicago Society for Neuroscience Meeting, Illinois

2014 Creation of Spliced-Variant forms of alpha-Synuclein for study in Yesat Models. S. Bello Rojas*, K. Hamid*, and S. DebBurman. Chicago Society for Neuroscience Meeting, Illinois

2013 Evidence of Endocytic Regulation of Alpha-Synuclein Aggregation and Toxicity: Insights from yeast.  M. Tembo*, M. Senagolage*, J. Perez*, A. Ayala*, S. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois
(First Prize to M. Tembo ’15, Undergraduate Poster)

2013 Creation of C-terminal Truncation Variants of Alpha-Synuclein to test for Parkinson’s Disease Relevance in Yeast.  C. Alvarado*, S. Chiren*, J. James*, A. Roman*, K. Campbell*, and S. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois

2013 Alpha-Synuclein Familial Mutants in Parkinson’s Disease: Unexpected A30P Dominance.  N. Kukulka*, S. DebBurman. Chicago Society for Neuroscience Meeting, Illinois
(Third Prize to N. Kukulka ’13, Undergraduate Poster)

2013 Identifying Specific Amino Acids in Parkinson’s Disease Protein Alpha-Synuclein that Control its Toxic Properties. K. Campbell*, K. Solvang*, M. Senagolage*, G. Lipkin*, S. DebBurman. Chicago Society for Neuroscience Meeting, Illinois

2012 Alpha-Synuclein Familial Mutants in Parkinson’s Disease: Does combining them aggravate pathological properties in yeast models? N. Kukulka*, R. Vlaar*, M. Herriges*, M. Senagolage*, S. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois

2012 Identifying Specific Amino Acids in Parkinson’s Disease Protein Alpha-Synuclein that Control its Toxic Properties. K. Campbell*, K. Solvang*, M. Senagolage*, G. Lipkin*, S. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois (Second Prize to K. Campbell ’14, Undergraduate Poster)

2012 Are multiple Parkinson’s disease mutants worse than one? N. Kukulka*, R. Vlaar*, S. DebBurman. Chicago Society for Neuroscience meeting, Illinois

2012 Seven Years of Eukaryon: An undergraduate scholarship journal that supports inquiry-based pedagogy & strengthens a community of undergraduate scholars. A. Reich*, M. Senagolage*, S. Rizvydeen*, A.  Konnikova*,  M Fiske*, S.  Davis*, S. Pore*, M. Zorniak*, K. Brandis*, S. Menke*, P.  Smith, S.K. DebBurman. Chicago Society for Neuroscience Meeting,  Illinois

2012 RAISING BRAIN AWARENESS: Integration Of Undergraduate Curriculum With Public Education & K-5 Outreach at Lake Forest College. K. Johnson*, D. Brutman*, M. Senagolage*, S.K. DebBurman. Chicago Society for Neuroscience Meeting, Illinois

2011 M. Senagolage*, J Perez*, A. Ayala*, M. Vahedi*, J. Price*, M. Fiske*, and S.K. DebBurman. Complex regulation of alpha-synuclein pathotoxic properties in yeasts by endocytosis genes.  Society for Neuroscience Meeting, Washington, DC
(M. Senagolage ’12 received both the 2011 Society for Neuroscience and the Faculty for Undergraduate Neuroscience Undergraduate Travel Awards )

2011 RAISING BRAIN AWARENESS: Integration Of Undergraduate Curriculum With Public Education & K-5 Outreach at Lake Forest College. D. Brutman*, M. Senagolage*, S.K. DebBurman. Society for Neuroscience Meeting, Washington, DC (D. Brutman ’12, Society for Neuroscience Brain Awareness Week Travel Award recipient)

2011 Eight Years of Eukaryon: An undergraduate scholarship journal that supports inquiry-based pedagogy & strengthens a community of undergraduate scholars. M. Senagolage*, S. Rizvydeen*, A.  Konnikova*,  M Fiske*, S.  Davis*, S. Pore*, M. Zorniak*, K. Brandis*, S. Menke*, P.  Smith, S.K. DebBurman. Society for Neuroscience Meeting, Washington, DC

2011 Evaluating the role of two post-translational modifications of Parkinson’s disease protein alpha-synuclein in yeast model. K Solvang* and S.K. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois (First Prize to K. Solvang ’11, Undergraduate Poster)

2011 Genetic support for endocytosis as degradation route for alpha-synuclein, the Parkinson’s disease protein. M. Senagolage*, J. Perez*, A. Ayala* & S.K. DebBurman. Chicago Society for Neuroscience meeting
(Second Prize to M. Senagolage ’12- Undergraduate poster)

2011 Deciphering Parkinson’s: Are multiple mutants worse than one? N. Kukulka*, M. Fiske*, K. Solvang*, S. DebBurman. Chicago Society for Neuroscience meeting.Annual Society for Neuroscience Meeting, Chicago, Illinois

2011 Evaluating the genetic link between autophagy and Parkinson’s disease in yeasts. A. Konnikova*, S. DebBurman. Chicago Society for Neuroscience meeting, Chicago, Illinois

2010 Insight Into Parkinson’s Disease: Is alpha-synuclein degraded by endocytosis? M. Senagolage*, J. Perez*, A. Ayala*, M. Vahedi*, J. Price* & S. Debburman. American Society of Cell Biology Meeting, Philadelphia, PA (M. Senagolage ’12, 2010 ASCB Undergraduate Travel Award recipient)

2010 Eukaryon: An undergraduate scholarship journal that supports inquiry-based pedagogy & strengthens a community of undergraduate scholars.? S. Rizvydeen*, M. Senagolage*, M.  Fiske*,  A.  Konnikova*,  S.  Davis*, P.  Smith; S. K. DebBurman. American Society of Cell Biology, Philadelphia, PA

2010 Evaluating Autophagic regulation of alpha-synuclein pathotoxicity properties in budding yeast. A. Konnikova*, R. Choi*, D. Sanchez*, K. Ahlstrand*, P. Sullivan*, Shubhik DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois (First Prize to A. Konnikova ’11, Undergraduate Poster)

2010 Insight Into Parkinson’s Disease: Is alpha-synuclein degraded by endocytosis? M. Senagolage*, J. Perez*,& S. Debburman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois

2010 Contributions of familial mutation E46K, phosphorylation, protein domains, and alanine-76 to alpha-synuclein toxicity in yeasts. M. Fiske*, Shubhik DebBurman. American Society of Biochemistry & Molecular Biology Meeting, Anaheim, California (First Prize Undergraduate Poster Award and UAN-ASBMB Travel Award to M. Fiske ’10)

2010 Eukaryon: An undergraduate scholarship journal that supports inquiry-based pedagogy & strengthens a community of undergraduate scholars. M.  Fiske*,  A.  Konnikova*,  S.  Davis*, P.  Smith, S. K. DebBurman. American Society of Biochemistry & Molecular Biology Meeting, Anaheim, California

2010 Evaluation of alpha-synuclein’s connection to novel UPP Genes in a yeast model for Parkinson’s disease. C. Becerra*, W. Press*, M. Fiske* and SK DebBurman. Chicago Chapter Society for Neuroscience Symposium, Chicago, Illinois

2010  Phosphorylation and Alanine-76 contribute to alpha-synuclein’s membrane association and aggregation. R. Brezinsky*, K. Solvang*, M. Fiske*, and SK DebBurman. Chicago Chapter Society for Neuroscience Symposium, Chicago, Illinois

2009 Autophagic regulation of alpha-synuclein pathotoxicity properties in budding yeast reveals unexpected complexities .?  A.  Konnikova*, D.  Sanchez*, R.  Choi*,  K.  Ahlstrand*, P.  Sullivan*, and  SK DebBurman. American Society of Cell Biology, San Diego, California

2009 Investigating the contribution of serine phosphorylation, alanine-76, and familial mutant E46K to alpha-synuclein pathotoxicity in two yeast models.? M.  Fiske*, K.  Solvang*, S.  Valtierra*, S.  Herrera*, M.  Zorniak*, A.  Konnikova*, and S. K. DebBurman. American Society of Cell Biology, San Diego, California

2009 An advanced cell biology course designed for undergraduates to propose, conduct, and publish original biomedical research.?  S.K. DebBurman and M.  Fiske*. American Society of Cell Biology, San Diego, California

2009 Eukaryon: An undergraduate scholarship journal that supports inquiry-based pedagogy & strengthens a community of undergraduate scholars. M.  Fiske*,  A.  Konnikova*,  S.  Davis*, P.  Smith, S. K. DebBurman. American Society of Cell Biology, San Diego, California

2009 Eukaryon: An undergraduate scholarship journal that supports inquiry-based pedagogy & strengthens a community of undergraduate scholars. P.  Smith, M.  Fiske*,  A. Konnikova*,  S.  Davis*, S. K. DebBurman. Society for Developmental Biology Meeting, San Francisco, California (John Doctor Education Prize to P. Smith)

2009 Evaluating autophagic regulation of alpha-synuclein pathotoxicity properties in budding yeast. A. Konnikova*, R. Choi*, D. Sanchez*, K. Ahlstrand*, P. Sullivan*, S.K. DebBurman. Annual Society for Neuroscience Meeting, Chicago, Illinois

2009 Unexpected complexity in endosome/MVB pathway-mediated regulation of alpha-synuclein localization, accumulation, and toxicity in budding yeast. J. Perez*, A. Ayala*, S.K. DebBurman
Annual Society for Neuroscience Meeting, Chicago, Illinois

2009 Investigating the contribution of serine phosphorylation and alanine-76 To alpha-synuclein aggregation, membrane association, and toxicity In two yeast models. M. Fiske*, K. Solvang*, M. White*, S. Valtierra*, S. Herrera*, M. Zorniak*, S.K. DebBurman. Annual Society for Neuroscience Meeting, Chicago, Illinois

2009  EUKARYON: The use of an undergraduate scholarship journal to strengthen inquiry-based pedagogy and a community of undergraduate scholars. M. Fiske*, A. Konnikova*, S. Davis*, P. Smith, S.K. DebBurman. Annual Society for Neuroscience Meeting, Chicago, Illinois

2009 Design of an advanced biology course wherein undergraduates propose, conduct, and publish original neuroscience research. S.K. DebBurman. Annual Society for Neuroscience Meeting, Chicago, Illinois

2009 Evaluation of alanine-76, serine phosphorylation, and lysosome-based degradation of alpha-synuclein in yeast models. M. Fiske*, A. Ayala*, R. Choi*, S.K. DebBurman. Gordon Conference “Stress Proteins in Growth Development & Disease”, Proctor Academy, Andover, New Hampshire (M. Fiske ’10 was awarded a Gordon Research Conference GRC Chair’s Award to attend and present this conference- he was the only undergraduate at this meeting).

2009 Investigating whether alanine-76 and serine phosphorylation contribute to alpha-synuclein aggregation, membrane association, and toxicity in yeasts. M. Fiske*, M. White*, S. Valtierra*, S. Herrera*, M. Zorniak*, A. Konnikova*, S.K. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois

2009  Evaluating autophagic regulation of alpha-synuclein in a budding yeast model. R.Choi*, M.White*, A. Konnikova*, J. McLain*, S.K.DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting, Chicago, Illinois

2009 Evaluating autophagic regulation of alpha-synuclein in a budding yeast model. R.Choi*, M.White*, A. Konnikova*, J. McLain*, S.K. DebBurman Chicago Chapter Society for Neuroscience Symposium, Chicago, Illinois (R.Choi ’09 awarded Third Prize, undergraduate poster).

2009 Investigating whether alanine-76 and serine phosphorylation contribute to alpha-synuclein aggregation, membrane association, and toxicity in yeasts. *M. Fiske, *M. White, *S. Valtierra, *S. Herrera, *M. Zorniak, *A. Konnikova, S.K. DebBurman. Chicago Chapter Society for Neuroscience Symposium, Chicago, Illinois.  (M. Fiske ’10 awarded First Prize, undergraduate poster)

2008 EUKARYON: The use of an undergraduate scholarship journal to strengthen inquiry-based pedagogy and a community of undergraduate scholars. S.K. DebBurman, *S. Davis, *M.  Fiske, P. Smith. American Society of Cell Biology Meeting, San Francisco, CA
 
2008 Investigation of endosome/MVB Pathway-mediated regulation of alpha-synuclein localization, accumulation, and toxicity in a yeast model reveals unexpected complexity. *A. Ayala, *M. White, S.K. DebBurman. American Society of Cell Biology Meeting, San Francisco, CA
 
2008 Investigating whether Alanine-76 and serine phosphorylation contribute to alpha-synuclein aggregation, membrane association, and toxicity in yeasts. *M. Fiske, *S. Valtierra, *S. Herrera, *M. White, *M. Zorniak, and S.K. DebBurman. American Society of Cell Biology Meeting, San Francisco, CA
 
2008 Evaluating autophagic regulation of alpha-synuclein in a budding yeast model. *R. Choi, *A. Konnikova, *J. McLain, *M. White, & S.K. DebBurman. American Society of Cell Biology Meeting, San Francisco, CA
 
2008 Yeasts shed light on alpha-synuclein hydrophobicity: Alanine-76 regulates aggregation & plasma Membrane binding. *M. Fiske, *S. Valtierra, *M.White, *M. Zorniak, and S.K. DebBurman. American Society for Pharmacological & Experimental Therapeutics-Great Lakes Chapter Meeting
 
2008 Evaluating the role of the multi-vesicular body/vacuole pathway in the regulation of alpha-synuclein aggregation and toxicity in budding yeast. *A. Ayala, *M. Vahedi, *J. Price, S.K. DebBurman. American Society for Pharmacological & Experimental Therapeutics-Great Lakes Chapter Meeting (A. Ayala ’09 awarded First Prize, undergraduate poster)
 
2008 Similarities and differences in alpha-synuclein properties within two yeast models: Analysis of E46K, A76E, & post-translation modification mutants. *S. Valtierra, *M.White, *M. Fiske, *S. Herrera, & S.K. DebBurman. Chicago Signal Transduction Symposium
 
2008 Evaluating alpha-synuclein concentration threshold and phospholipid composition to induce aggregation, membrane localization and toxicity in yeast. *L. Kukreja, *S. Valtierra, S.K. DebBurman. Chicago Signal Transduction Symposium
 
2008 Similarities and differences in alpha-synuclein properties within two yeast models: Analysis of E46K, A76E, & post-translation modification mutants. *S. Valtierra, *M.White, *M. Fiske, *S. Herrera, & S.K. DebBurman, Chicago Society for Neuroscience Symposium (S. Valtierra ’08 awarded Second Prize- undergraduate poster)
 
2008 Evaluating the role of the multi-vesicular body/vacuole pathway in the regulation of alpha-synuclein aggregation and toxicity in budding yeast. *A. Ayala, *M. Vahedi, *J. Price, Shubhik DebBurman. Chicago Society for Neuroscience Symposium (A. Ayala ’09 received Honorable Mention- undergraduate poster)
 
2007 Evaluation of E46K & A76E alpha-synuclein aggregation and toxicity In budding & fission Yeasts. *S. Valtierra, *M.White, *M. Zorniak, *S. Herrera, *M. Fiske, & S.K. DebBurman. American Society of Cell Biology Meeting, Washington DC (S. Valteirra ’08 awarded First Prize- ASCB MAC undergraduate poster)
 
2007 Evaluating alpha-synuclein concentration threshold and phospholipid composition to induce aggregation, membrane localization and toxicity in yeast. *L. Kukreja, *S. Valtierra, S.K. DebBurman. American Society of Cell Biology Meeting, Washington DC (L. Kukreja ’08 was a 2010 ASCB undergraduate travel Award recipient)
 
2007 Evaluating the role of the multi-vesicular body/vacuole pathway in the regulation of alpha-synuclein aggregation and toxicity in budding yeast. *A. Ayala, *M. Vahedi, *J. Price, Shubhik DebBurman. American Society of Cell Biology Meeting, Washington DC

2007 Budding yeast model for Parkinson disease. *M. White, *M.Zorniak, *L. Kukreja, *A. Ayala, *M. Fiske, S.K. DebBurman
Gordon Conference “Stress Proteins in Growth Development & Disease”, Oxford University, UK (M. White ’07 was awarded a Gordon Research Conference GRC Chair’s Award to attend and present this conference- he was the only undergraduate at this meeting).
         
2007 Fission yeast model for Parkinson disease. S.K. DebBurman, *L. Kukreja, *K. Brandis, *M. Zorniak, *S. Valtierra. Gordon Conference “Stress Proteins in Growth Development & Disease”, Oxford University, UK

2007 Students as scholars: Design of an advanced cell biology course wherein undergraduates propose, conduct, and publish original research. S.K. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting          

2007 EUKARYON: Design, publication, and governanance of a student peer-reviewed undergraduate journal of life science scholarship at Lake Forest College. S.K. DebBurman, *M.Zorniak, *A. Spivak, *C. Bueter, *M. Mckinzey. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting          

2007 The newest familial Parkinson disease mutant E46K Alpha-Synuclein is selectively toxic to yeast. *M.White, S.K. DebBurman
Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting

2007 In Parkinson disease, What happens to your brain when energy generators crash? *M.Zorniak, S.K. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting    

2007 ALPHA-SYNUCLEIN FISSION YEAST MODEL: Live cell evidence for threshold concentration for aggregation. *L. Kukreja, *K. Brandis, S.K. DebBurman. Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics meeting

2007 ALPHA-SYNUCLEIN FISSION YEAST MODEL: Live cell evidence for threshold concentration for aggregation. *L. Kukreja, *K. Brandis, S.K. DebBurman. Chicago Signal Transduction Symposium

2007 The newest familial Parkinson disease Mutant E46K Alpha-Synuclein is selectively toxic to yeast. *M.White, S.K. DebBurman
Chicago Signal Transduction Symposium

2007 EUKARYON: Design, publication, and governanance of a student peer-reviewed undergraduate journal of life science scholarship at Lake Forest College. S.K. DebBurman, *M.Zorniak, *A. Spivak, *C. Bueter, *M. Mckinzey. Chicago Signal Transduction Symposium   

2007 The newest Familial Parkinson disease mutant E46K Alpha-Synuclein is selectively toxic to yeast. *M.White, S.K. DebBurman 
Chicago Society for Neuroscience Symposium  (M. White ’07 awarded SECOND PRIZE, undergraduate poster competition)
           
2007 ALPHA-SYNUCLEIN FISSION YEAST MODEL: Live cell evidence for threshold concentration for aggregation. *L. Kukreja, *K. Brandis, S.K. DebBurman. Chicago Society for Neuroscience Symposium

2006 BUDDING YEAST MODEL FOR ALPHA-SYNUCLEIN: Evaluation of E46K toxicity, catalase deletion, & multivesicular body (MVB) formation. *M. White, *M.Zorniak, *M. Vahedi, *S. Herrera, *K. Brandis, S.K. DebBurman. American Society of Cell Biology Meeting, San Francisco

2006 ALPHA-SYNUCLEIN FISSION YEAST MODEL: Live cell evidence for  threshold concentration for aggregation. *L. Kukreja, *K. Brandis, S.K. DebBurman. American Society of Cell Biology Meeting, San Francisco (L. Kukreja ’10 received an ASCB Travel Award to attend the meeting)

2006 Live cell evidence to support nucleation polymerization model for alpha-synuclein toxicity: Concentration is key. *L. Kukreja, *K. Brandis, S.K. DebBurman.  Chicago Society for Neuroscience Symposium

2005  Alpha-SYNUCLEIN FISSION YEAST MODEL: Concentration-dependent aggregation without membrane localization or toxicity”
*K. Brandis, *I. Holmes, *S. England, *N. Sharma, S.K. DebBurman American Society of Cell Biology Meeting, San Francisco, CA

2005 “Alpha-SYNUCLEIN BUDDING YEAST MODEL: Toxicity enhanced by impaired proteasome and qxidative stress” *T. Vaidya, *K. Brandis, *S. Herrera, *N. Sharma, B. Johnson, S.K. DebBurman American Society of Cell Biology Meeting, San Francisco, CA

2005 “EUKARYON: An undergraduate journal of life science scholarship at Lake Forest College” *K. Brandis, *T. Vaidya, & S.K. DebBurman American Society of Cell Biology Meeting, San Francisco, CA

2005 “Design of a cell Biology course wherein undergraduates propose, conduct, and publish original research”. American Society of Cell Biology Meeting, San Francisco, CA

2005 “Fission yeast recapitulate alpha-synuclein misfolding”
*K. Brandis, *I. Holmes, *S. England, S.K. DebBurman Experimental Biology, San Diego, CA (K. Brandis ’06 received an ASBMB Travel Award to attend the meeting)

2005 “Budding yeast model for alpha-synuclein: Evaluating E46K mutant, post-translational modification,  & ubiquitin conjugating enzyme specificity”. *S. Herrera ’05, *N. Sharma ’04, *B Johnson ’03, *K. Brandis ’06, *R. Shrestha ’07, *M. Stevenson ’06, S.K. DebBurman. Experimental Biology, San Diego, CA (S. Herrera ’05 received an ASBMB Travel Award to attend the meeting)

2005 “Design of a cell biology course wherein undergraduates propose, conduct, and publish original research”. Experimental Biology, San Diego, CA

2005 “Fission yeast recapitulate alpha-synuclein misfolding”
*K. Brandis ’06, *I. Holmes ’05, *S. England ’04, S.K. DebBurman Chicago Signal Trandsuction Symposium, IL

2005 “Budding yeast model for alpha-synuclein: Evaluating E46K mutant, post-translational modification,  & ubiquitin conjugating enzyme specificity” *S. Herrera ’05, *N. Sharma ’04, *B. Johnson ’03, *K. Brandis ’06, *R. Shrestha’07, *M. Stevenson ’06, S.K. DebBurman. Chicago Signal Trandsuction Symposium, IL

2005 “EUKARYON: A Undergraduate journal of life science scholarship at Lake Forest College” *T. Vaidya ’07, S.K. DebBurman. Chicago Signal Trandsuction Symposium, IL

2005 “Budding yeast model for alpha-synuclein: Evaluating E46K mutant, post-translational modification,  & ubiquitin conjugating enzyme specificity” *S. Herrera ’05, *N. Sharma ’04, *B. Johnson ’03, *K. Brandis ’05, *R. Shrestha ’07, *M. Stevenson ’07, S.K. DebBurman. Chicago Society for Neuroscience Symposium, IL

2005 “Evaluating STP2-dependent alpha-synuclein toxicity in yeast: A role for GAPDH?” *A. Paul ’04, *R. Shrestha ’07, S.K. DebBurman. Chicago Society for Neuroscience Symposium, IL (A. Paul ’05 received First Prize in the meeting’s undergraduate research competition)

2004 “Fission yeast recapitulate alpha-synuclein misfolding”.
*I. Holmes ’05, *K. Brandis ’06, *S. England ’04, S.K. DebBurman. American Society of Cell Biology Meeting, Washington DC

2004 “Evaluating protein degradation pathway and post-translational modification in regulating alpha-synuclein” misfolding in yeast. *S. Herrera ’05, *N. Sharma ’04, *B Johnson ’03, *K. Brandis ’06, R. Shrestha ’07, *M. Stevenson ’06, S.K. DebBurman. American Society of Cell Biology Meeting, Washington DC (S. Herrera ’05 received an National Institute of Aging Travel Award to attend this meeting and won the First Prize at the meeting’s MAC research symposium)

2004 “Fission Yeast Recapitulate Alpha-Synuclein Misfolding”
*I. Holmes ’05, *K. Brandis ’04, *S. England ’04, SK DebBurman Society for Neuroscience, San Diego, CA

2004 “Evaluating Protein Degradation Pathway and Post-translational Modification in Regulating Alpha-Synuclein” Misfolding in Yeast. *S. Herrera, *N. Sharma, *B Johnson, S.K. DebBurman. Society for Neuroscience, San Diego, CA

2004 “Alpha-synuclein localizes to cell membrane and forms cytoplasmic aggregates in baker’s yeast”. *N. Sharma ’04, *B. Johnson ’03, *S. Herrera ’05, Shubhik DebBurman Annual Meeting of the American Society of Biochemistry & Molecular Biology, Boston, MA (N. Sharma ’04 received an ASBMB Travel Award to attend the meeting and won the First Prize at its undergraduate poster competition )

2004 “Schizosaccharomyces Pombe Model Recapitulates Alpha-Synuclein Misfolding”. *I. Holmes ’05, *S. England ’04, *K. Brandis ’05, Shubhik DebBurman Annual Meeting of the American Society of Biochemistry & Molecular Biology, Boston, MA (I. Holmes ’05 received an ASBMB Travel Award to attend the meeting)

2004 “Undergraduate appreciation for research in medicine: Role-playing projects using primary literature”. Annual Meeting of the American Society of Biochemistry & Molecular Biology, Boston, MA

2004 “Alpha-synuclein localizes to cell membrane and forms cytoplasmic aggregates in baker’s yeast”. *N. Sharma ’04, *B. Johnson ’03, *S. Herrera ’05, Shubhik DebBurman Chicago Signal Transduction Symposium, IL

2004 “Schizosaccharomyces pombe models alpha-synuclein misfolding and supports the nucleation polymerization hypothesis” *I. Holmes ’05, *S. England ’04, K. Brandis ’05. S.K. DebBurman Chicago Signal Transduction Symposium, IL

2004 “Utilizing genetic and live cell microscopy tools to study alpha-synuclein misfolding in two yeasts” *N. Sharma ’04, *I. Holmes ’05, S.K. DebBurman. Posters on the Hill, Council of Undergraduate Research Symposium, Washington, DC

2004 “Alpha-synuclein localizes to cell membrane and forms cytoplasmic aggregates in baker’s yeast”. *N. Sharma ’04, *B. Johnson ’03, *S. Herrera ’05, S.K. DebBurman.  Annual Meeting of the Chicago Chapter Society for Neuroscience, IL

2004 “Schizosaccharomyces pombe models alpha-synuclein misfolding and supports the nucleation polymerization hypothesis”
*I. Holmes ’05, *S. England ’04, Katrina Brandis ’05, S.K. DebBurman Annual Meeting of the Chicago Chapter Society for Neuroscience, IL (I. Holmes ’05 received First Prize at the meeting’s undergraduate research competition)

2004 “Igniting undergraduate appreciation for neuroscience research in medicine: Role-playing projects using primary literature” Annual Meeting of the Chicago Chapter Society for Neuroscience, IL

2003 “Two yeast models for protein misfolding associated with Parkinson’s disease” *N. Sharma ’04, *S. England ’05, *K. Brandis ’06, *I. Holmes ’05,  *B. Johnson ’03, S.K. DebBurman. Annual Meeting of the American Society of Cell Biology

2003 “Appreciating the role of research In medicine & society: Experiential research projects for beginning, intermediate, and advanced undergraduates” Annual Meeting of the American Society of Cell Biology

2003 “Developing a yeast model for protein misfolding linked to Parkinson’s disease: Expression, & biochemical studies of wildtype & mutant forms of human alpha-synuclein” *N. Sharma, *S. England, *B Johnson, S.K. DebBurman. Chicago Signal Transduction Symposium

2003 “Expression of wildtype and mutant alpha-synuclein in baker’s yeast” *B. Johnson ’03, *N. Sharma ’04, Shubhik DebBurman. American Society of Biochemistry & Molecular Biology Meeting (Brandon Johnson ’03 received an ASBMB Travel Award to attend this meeting)

2003 “THINKING LIKE A SCIENTIST: Experiential Research Projects To Promote Undergraduate Biology Learning And Scientific Process”
Shubhik DebBurman, *M. McNeeley, *A Eakley. American Society of Biochemistry & Molecular Biology Meeting

2003 “Expression of wildtype and mutant alpha-synuclein in Baker’s Yeast” *N. Sharma, *B. Johnson, Shubhik DebBurman. Chicago Chapter Society for Neuroscience Meeting (N. Sharma ’04 received Third Prize at the meeting’s undergraduate research competition)

2003 “Learning How Scientists Think: Experiential Teaching and Learning in an Undergraduate Neuroscience Course” *M. McNeeley, *A Eakley, Shubhik DebBurman. Annual Meeting of the Chicago Chapter Society for Neuroscience

2002 “Learning How Scientists Work: Experiential research projects to promote cell biology learning and scientific process skills”, Annual Meeting of the American Society of Cell Biology

2002 “Experiential research projects requiring primary article mastery promotes student learning in an undergraduate neurobiology course”
Annual Meeting of the Society of Neuroscience

2002 “Experiential research projects promote learning an inquiry-based undergraduate science curriculum”, Annual Meeting of the American Society of Molecular Biology & Biochemistry

2000 “Chaperone-promoted solubilization of protease-resistant prion protein”  Chicago Signal Transduction Symposium, Chicago, IL

2000 “Experiential projects promote learning via mastery of primary articles in two undergraduate cell biology courses” Annual Meeting of American Society of Cell Biology, San Francisco, CA

2000 “Chaperone-promoted solubilization of protease-resistant prion protein” Annual Meeting of American Society of Molecular Biology & Biochemistry, Boston, MA

2000 “Mastering primary articles: two experiential projects that facilitate learning among science undergraduate majors” Annual Meeting of American Society of Molecular Biology & Biochemistry, Boston, MA

1998 “Chaperone-promoted solubilization of PrP-res, the infectious element in transmissible spongiform encephalopathies”, American Society of Cell Biology Meeting, San Francisco, CA

1998 “Chaperone-assisted formation of mammalian prions” Annual Midwest Chaperone & Stress Response Meeting, Northwestern University, Evanston, IL

1997 “Chaperone-supervised misfolding of the prion protein to its protease-resistant aggregated form” Annual meeting of the Life Sciences Research Foundation, Baltimore, MD

1997 “Chaperone-promoted misfolding of the cellular prion protein”
Annual Life Science Departmental Retreat, The University of Chicago, Chicago, IL

1997 “Will prion chaperones control the madness?”, Annual Minisymposium on Cancer Biology, University of Chicago, IL

1996 “G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that is conditionally activated by G protein beta-gamma subunits”, Annual meeting of American Society for Pharmaceutical and Experimental Therapeutics-Great Lakes Chapter, Chicago, IL

1995 “Lipid-mediated regulation of G protein-coupled receptor kinases GRK2 & GRK3”, International Symposium of Muscarinic Receptor Subtypes and Signaling, Ft. Lauderdale, FL

1995 “Lipid-mediated regulation of G protein-coupled receptor kinases GRK2 & GRK3”, Annual meeting of the Society for Neuroscience-Chicago Chapter, Chicago, IL

1995 “Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases”  Annual meeting of American Society for Pharmaceutical and Experimental Therapeutics-Great Lakes Chapter, Chicago, IL

1994 “Lipid-mediated regulation of G protein-coupled receptor kinases GRK2 & GRK3”  Annual Meeting of the Society for Neuroscience, Miami Beach, FL

1994 “Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases”  Annual Meeting of the Society for Biophysics, New Orleans

Public Work

How Does Our Brain Work: Sensing, Integrating, Acting” (2010, Spring 2012, Fall 2012) Teaching outreach for elementary school children by first-year neuroscience students through partnership with North Chicago schools

Making sense our our brain” (2008, 2010, 2012)
Teaching outreach for Montessori children through partnership with Forest Bluff School

Medical Mysteries of the Mind: LFC Brain Awareness Week
( 2003, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013)
Organized public brain outreach campaigns at Lake Forest College featuring work of  Lake Forest College students and highlighting neuroscience research by Lake Forest College faculty and neuroscience leaders in the Chicago research community

NeuroFrontiers Workshops” (2001, 2002, 2003, 2006, 2008, 2009, 2010, 2011, 2012, 2013) Annually organize a public neuroscience workshop where Lake Forest College students role-play the world leaders of neuroscience and educate the community about advances in brain science.

The Hostage Brain Symposium” (2010, 2012) Annually organize a public biology workshop where Lake Forest College BIO362 Mechanism of Brain Dysfunction students educate the community on advances in medicine and human diseases.

The Diseased Genome Symposia” (2002, 2003, 2005, 2006, 2007, 2009) Annually organize a public biology workshop where Lake Forest College BIO221 cell and molecular biology students educate the community on advances in medicine and human diseases.

Why Do Research: From Revealing Protein Shapes To Curing Tragic Diseases” (2001) organized a session for college-bound minority high school students, funded by Howard Hughes Medical Institute funded “Art of Science and Medicine” residential workshop, Kalamazoo, Michigan

Cholera in Kalamazoo in the 1850s” (2000)
English Department, Kalamazoo College, Michigan

Bad Company: Chaperone proteins helps perverts innocent proteins” (1998) Lay Science Article Featured in 1998-99 American Society of Cell Biology Press Book (selected as one of ten noteworthy cell biology research abstracts); http://www.faseb.org/ascb/meetings/pressbk98.pdf)

Undergraduate Mentoring

Laura Maxson ’00*, MA
Dr. Dan Appledorn ’00*, PhD
Dr. Aash Bhatt ’01*, MD
Dr. Geetha Athappilly ’01*, MD
Dr. Anne Hinz ’02*, MD
Ryan Paulsen ’02, Senior Thesis
Dr. Brandon Johnson ’03, PhD, Senior Thesis
Dr. Samantha England ’04, PhD
Dr. Nijee Sharma ’04, MD/PhD, Senior Thesis**
Rity Upadhyaya ’04, pursuing Masters studies
Dr. Isaac Holmes ’05, MD
Dr. Sara Herrera ’05, MD, Senior Thesis
Adam Hanig ’05
Dr. Olga Mikhaylov ’05, MD
Dr. Arun Paul ’05, PhD, MD
Dr. David Mann ’06, MD, Senior Thesis
Dr. Katrina Brandis ’06, PhD, Senior Thesis**
Melissa Stevenson ’06, Physican Assistant
Jessica Price ’06, MA, pursuing PhD studies
Dr. Ruja Srestha ’07, PhD
Dr. Tulaza Vaidya ’07, PhD
Dr. Michael White ’07, MD, Senior Thesis
Dr. Michael Zorniak ’07, PhD, Senior Thesis
Lokesh Kukreja ’08, pursuing PhD studies, Senior Thesis
Dr. Mithaq Vahedi ’08, MD
Sina Vahedi ’08, pursuing MD studies
Stephanie Valtierra ’08, pursuing PhD studies, Senior Thesis
Tasneem Saylawalla ’08
Lavinia Sinitean ’08
Alexandra Ayala ’09,Teach for America,  Senior Thesis
Dr. Ray Choi ’09, MD, Senior Thesis
Nengding Wang ’09, pursuing PhD studies
Daryn Cass ’10, pursuing MD studies, Senior Thesis
Michael Fiske ’10, pursuing PhD studies, Senior Thesis**
Jaime Perez ’10, MA Prosthetics, Senior Thesis
Carlos Becerra ’10
Rebecca Brezinsky ’11, pursuing DVM studies
Alina Konnikova ’11, pursuing MD studies, Senior Thesis
Julian McLain ’11
Will Press ’11
Daniel Sanchez ’11
Keith Solvang ’11, pursuing MD studies, Senior Thesis
Kayla Ahlstrand ’12, pursuing DVM studies
Madhavi Senagolage ’12, pursuing PhD studies, Senior Thesis
Pete Sullivan ’12, pursuing PhD studies, Senior Thesis
Daniella Brutman ’12, pursuing MD studies, Senior Thesis
Natalie Kukulka ’13, Senior Thesis
Ashley Reich ’13, Senior Thesis
Kim Diah ’13, Senior Thesis
Katrina Campbell ’14, Senior Thesis
Anhar Mohamed ’14, Senior Thesis
Rida Khan ’14
Ryan Vlaar ’14
Michael Herriges ’15
Galina Lipkin ’15
Maiwase Tembo ’15
Charles Alvarado ’16
Saul Bello Rojas ’16
Sarah Chiren ’16
Khadijah Hamid ’16
Jyothis James ’16
Maribel Munoz ’16
Alexandra Roman ’16
Logan Graham ’17
Cam Gudmundson ’17
Ana McCracken ’17
Peyton Schrag ’17

*Kalamazoo College students
**Phi Beta Kappa Senior Thesis Award
Senior Thesis (= Committee chair)